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In this legal case related to the Engle progeny tobacco litigation, Thomas and Bettye Ryan allege that the tobacco companies being sued deliberately obscured the risks associated with smoking, contributing to nicotine addiction and the development of smoking-related health issues

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Despite the availability of techniques capable of quantifying the activity of CYP isozymes such as 1A2, 2B6, 2C9 and 3A4 [8], they are not commonly used in clinical practice

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